The 20-story, 650-room hotel included a top-floor ballroom, which featured a tall vaulted ceiling and corinthian columns.

In 1966, the building was renamed the Gateway Hotel. It remained open until 1987 when it was closed for renovation. It never reopened. The building remained vacated and became subject to decay and fires until 1999, when the City of St. Louis received funding to clean up the building for redevelopment.

In 2000, a public-private partnership between the Historic Restoration, Inc. of New Orleans, the City of St. Louis, and the State of Missouri made an agreement with Kimberly Clark Corporation and Marriott. Currently, the hotel is under construction along with the Lennox Hotel to become part of the Marriott Renaissance complex, which will serve the Convention Center in downtown St. Louis. The Gateway Hotel will see a complete renovation and a new 38-story tower will be built to the rear of the building. The hotel will be renamed the Renaissance Grand Hotel. It is expected to open in December of 2002.